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The conversion of porcine insulin to human insulin is achieved by ____________ reaction.

Correct Answer: transpeptidation
The conversion of porcine insulin to human insulin is achieved by transpeptidation reaction which replaces C-terminal alanine (β30) residue by a threonine by use of trypsin in an aqueous solution with an organic co-solvent. The protective group can be simply removed later by mild hydrolysis and the product purified by silica gel chromatography.

"Too often we try to solve human problem with non-human tools and in terms of non-human data. It is my simple thesis that a human problem requires a human solution. First we have to learn to recognise a human problem when we see one; and second, upon recognising it, we have to learn to deal with it as such and not as it were something else. A human problem to be brought to a human solution requires human data and human tools". Who said this?

The conversion of porcine insulin to human insulin is catalyzed by ________ enzyme.

The difference between human insulin and porcine insulin is located in which amino acid?

For the reaction, A = X + Y, the respective concentrations are CA, CX and CY. The forward reaction rate constant is kf and the backward reaction rate constant is kb. Choose the correct statement from the following:
P. At equilibrium, kf CA > kB CxCy
Q. If the reaction is irreversible than, kb CXCY = 0
R. The backward reaction rate will essentially be first order, if the forward reaction rate is first order.
S. Activation energy for the first order forward reaction will be independent of temperature.

Which type of porcine insulin is used in the treatment of diabetes mellitus?

For a reaction, the extent of reaction equation is Ni = Nio + ϒVi is Where: Ni = Moles of species I present in the system after the reaction occurs Nio = Moles of species I present in the system when the reaction starts Vi = Stoichiometric coefficient for species i in the specified chemical reaction equation ϒ = Extent of reaction

Rate constant for a first order reaction does not depend upon reaction time, extent of reaction and the initial concentration of reactants ; but it is a function of reaction temperature. In a chemical reaction, the time required to reduce the concentration of reactant from 100 gm moles/litre to 50 gm moles/litre is same as that required to reduce it from 2 gm moles/litre to 1 gm mole/litre in the same volume. Then the order of this reaction is

In the reaction,
Basics of Organic Reaction Mechanism mcq question image
if the concentration of both the reagents is doubled then the rate of the reaction will

A reaction of first order takes 10 minutes to achieve 50% conversion. The conversion achieved after 20 minutes is ____

Which of the following are covered under the scope of human resource management?
1. Forecasting human resource needs
2. Replacement planning
3. Human resource dynamics
4. Human resource development planning
5. Human resource audit
Select the correct answer: