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Consider the following statements regarding chain elongation during DNA synthesis and choose the correct answer:<br>1. The separated strands are kept open by DNA binding proteins (DBPs)<br>2. A DNA chain is initiated on the 3'- OH end of the primer<br>3. Okazaki fragments are synthesized on one strand; there is continuous DNA synthesis in the other strand<br>4. Okazaki fragments are joined by endonuclease
A
1, 2, 3 and 4 are true
B
Only 2, 3 and 4 are true
C
Only 1, 2 and 3 are true
D
Only 1, 3 and 4 are true
Correct Answer:
Only 1, 2 and 3 are true
Consider the following statements regarding DNA replication and choose the correct answer:
1. The very first requirement of DNA synthesis is the presence of a template or plan along which the new strand is to be constructed
2. The second requirement is of a DNA-dependent-DNA polymerase or simply DNA polymerase enzyme
3. A DNA Pol cannot join two free nucleotides; one of them must be anchored by hydrogen bonds to a DNA strand
4. Replication takes place bidirectionally
A
1, 2, 3 and 4 are true
B
Only 2 and 4 are true
C
Oniy 2, 3 and 4 are true
D
Only 1 and 2 are true
You transcribe a gene and obtain mRNA. To detect which strand is transcribed you replicate each strand in vitro and use the newly synthesized strand for hybridization with mRNA. If mRNA hybridize with the newly replicated strand from 1st strand then the gene transcribed was in ________
A
1st strand
B
2nd strand
C
Same copy in both strands
D
Dispersed
Ligation enzymes are used for ligating newly synthesized okazaki fragments. What holds true for okazaki fragments?
A
Okazaki fragments are short fragments of DNA formed on the leading strand
B
Okazaki fragments are large fragments of DNA formed on the lagging strand
C
Okazaki fragments are short fragments of DNA formed on the lagging strand
D
Okazaki fragments are large fragments of DNA formed on the leading strand
Consider the following statements regarding cell cycle and choose the correct answer:
1. During G
1
phase the cell grows in size and there is an active synthesis of RNA and proteins
2. The third stage of the cell cycle is termed G
2
phase
3. In the mitotic phase, the DNA molecule of each chromosome replicates by the synthesis of a new DNA molecule on the template of the existing DNA
A
Only 1 and 2 are correct
B
Only 2 and 3 are correct
C
Only 3 is correct
D
Only 1 and 3 are correct
Consider the following statements and choose the correct answer:
1. Adenine pairs with thymine (A : T) and guanine with cytosine $$\left( {G \vdots C} \right)$$
2. Adenine and thymine are joined by three hydrogen bonds through atoms
3. Guanine and cytosine are joined by two hydrogen bonds through atoms
4. The weak hydrogen bonding enables the two strands of the DNA to separate during replication
A
Only 1 and 2 are true
B
Only 2 and 3 are true
C
Only 3 and 4 are true
D
Only 1 and 4 are true
Which enzyme joins the Okazaki fragments into a continuous strand?
A
gyrase
B
topoisomerase
C
ligase
D
helicase
Consider the following statements regarding the DNA-mediated gene transfer and choose the correct answer:
1. DNA fragments carrying the gene to be transferred are mixed with a carrier DNA
2. They are then precipitated out with a calcium phosphate buffer
3. The precipitate is used to transform target cells
4. The Ca-precipitated DNA enters the cell by exocytosis
A
Only 1, 2 and 4 are true
B
Only 3 and 4 are true
C
Only 2, 3 and 4 life true
D
Only 1, 2 and 3 are true
Mean Value theorem is applicable to the and continuous in open interval (a, b) b) Functions continuous in closed interval only and having same value at point ‘a’ and ‘b’ c) Functions continuous in closed interval and differentiable in open interval (a, b) d) Functions differentiable in open interval (a, b) only and having same value at point ‘a’ and ‘b’
A
Functions differentiable in closed interval and continuous in open interval (a,
B
a, b
C
a, b
D
a, b
The process of transforming the discontinuous fragments (Okazaki fragments) into a continuous molecule is referred to as
A
Transformation
B
Maturation
C
Transposition
D
Transcription
Consider the following statements regarding the laws of evolution from Lamarck's thesis and choose the correct answer:
1. The internal forces of life tend to increase the size of an organism not only as a whole but in every part as well
2. Each organ or part is the outcome of the new movement which in turn is initiated by a new and continuous need or want
3. All that has been acquired by an individual organism during its lifetime is transmitted by heredity to its offsprings in the next generation
A
1, 2 and 3 are correct
B
Only 1 and 2 are correct
C
Only 2 and 3 are correct
D
Only 3 is correct