Which of the following cytokine is not released by Cytotoxic CD8+ T cells in order to carry out host defence mechanisms?

Correct Answer: TGF-β
Three of the most important cytokines released by cytotoxic CD8+ T cells are IFN-γ, TNF-α and TNF-β. IFN-γ directly inhibits viral replication as well as it enhances the expression of MHC class I and the molecules which are involved in peptide loading of the newly synthesized MHC class I proteins in infected cells. It also helps in activating macrophages by recruiting them to sites of infection both as effector cells and as antigen-presenting cells. TNF-α and TNF-β combine and interact with IFN-γ in order to activate macrophages. They also help in killing some target cells.