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What is the ratio of CD4+ cells to CD8+ cells?
A
1:2
B
2:5
C
2:1
D
1:5
Correct Answer:
2:1
The CD4+ cells are Helper T cells and CD8+ cells are the Cytotoxic T cells. Both of these cells are present in the ratio of 2:1.
Which of the following statement(s) is/are CORRECT for antigen activated effector T cells?
P. CD4+ cells make contact with macrophages and stimulate their microbicidal activity.
Q. CD4+ cells make contact with B cells and stimulate them to differentiate into plasma cells.
R. CD8+ cells make contact with B cells and stimulate them to differentiate into plasma cells.
S. CD8+ cells make contact with virus infected cells and kill them.
A
Q only
B
Q and S only
C
P, Q and S only
D
P, Q, R and S
Lineage commitment is a process in which CD4–CD8– (double negative) thymocytes differentiate to CD4– and/or CD8– T cells.
A
True
B
False
CD11b+CD4+CD8–DCs belong to which type of dendritic cells?
A
Blood DCs
B
Splenic DCs
C
Antigenic DCs
D
Skin DCs
The thymocytes that express both CD4 and CD8 surface markers are called as ________
A
Single Positive
B
Double Positive
C
Positive Selected
D
Double Selected
Thymocytes that express only one of CD4 or CD8 surface markers are called as _______
A
Single Negative
B
Double Negative
C
Single Positive
D
Double Positive
Which of the following statements are correct regarding common differences between plant and animal cells?
1. Plant cells have cellulose cell wall, while animal cells lack it.
2. Plant cells lack plasma membrane, while animal cells have it.
3. Mature plant cell have a large vacuole, while animal cells have numerous small vacuoles.
A
1 and 2
B
2 and 3
C
1 and 3
D
1, 2 and 3
CD8 T cells proliferate and initially differentiate into which type of lymphocyte?
A
Helper T lymphocyte (Th)
B
Cytotoxic T lymphocyte (CTL)
C
Memory T lymphocyte
D
Regulatory T lymphocyte
Which of the following cytokine is not released by Cytotoxic CD8+ T cells in order to carry out host defence mechanisms?
A
IFN-γ
B
TNF-α
C
TGF-β
D
TNF-β
Which MHC molecule recognizes CD8 TC cells?
A
MHC I
B
MHC II
C
MHC III
D
HLA-C
Methods of CD4-positive cells counting in HIV infected patients are
A
Flow cytometry
B
Microchip CD4 counting methods
C
Immunoelectrophoresis
D
Agglutination test
E
ELISA