Why is the introduction of genetically engineered lymphocytes into an ADA deficiency patient not a permanent cure? Suggest a possible permanent cure.
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Introduction of genetically engineered lymphocytes into a ADA deficiency patient is not a permanent cure because these cells are not immortal and the patient requires periodic infusion of such genetically engineered lymphocytes. A possible permanent cure can be isolating the gene producing adenosine deaminase (ADA) from bone marrow cells and introducing it into cells at early embryonic stages.