Describe the formation of Acetyl Co-A in respiration.


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1. The conversion of pyruvic acid to acetyl CoA is an oxidative decarboxylation reaction. 

2. It is catalyzed by a multienzyme complex-pyruvate dehydrogenase complex (PDH). This enzyme is present in mitochondria of eukaryotes and cytosol of prokaryotes. 

3. This reaction is called as ‘connecting link’ reaction between glycolysis and Krebs cycle.

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