The Apostolic Vicariate of Anatolia is a Roman Catholic Latin apostolic vicariate in the eastern half of Anatolia.
The missionary pre-diocesan jurisdiction is not part of any ecclesiastical province. It is under the direction of the Congregation for the Oriental Churches, an unusual structure for a Latin see, and directly dependent on the Holy See.
Its cathedral seat is the Marian Cathedral of the Annunciation in İskenderun. It has the Co-Cathedral of St. Anthony of Padua in Mersin as well.