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The term directed evolution is used within the transhumanist community to refer to the idea of applying the principles of directed evolution and experimental evolution to the control of human evolution. In this sense, it is distinct from the use of the term in biochemistry, which refers only to the evolution of proteins and RNA. Maxwell J. Melhmanh has described directed evolution of humans as the Holy Grail of transhumanism.Oxford philosopher Julian Savulescu wrote that:

Humanity until this point has been a story of evolution for the survival genes - survival and reproduction... we are entering a new phase of human evolution—evolution under reason—where human beings are masters of their destiny. Power has been transferred from nature to science.

According to UCLA biophysicist Gregory Stock:

Humanity is leaving its childhood and moving into its adolescence as its powers infuse into realms hitherto beyond our reach.

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