In a graph of rate of excretion versus plasma drug concentration, which kind of drug will give the below shown curve? (x axis- rate of excretion, y axis – plasma drug concentration)

Correct Answer: Drug filtered and actively reabsorbed
The drugs which are secreted or reabsorbed, the rate increases with an increase in plasma concentration to a point where saturation occurs. Drugs which are actively reabsorbed, excretion is negligible at low plasma concentration. These agents are excreted in urine when their glomerular filtrate concentration exceeds the active reabsorption capacity e.g. glucose.