If we are having sequence data for a particular organism, but screening is carried out for homologues the program used is BLAST.

Seven people A, B, C, D, E, F and G live on separate floors of a 7-floor building. Ground floor is numbered 1, first floor is numbered. 2 and so on until the topmost floor is numbered 7. Each one of these having a different cars-Cadillac, Ambassador, Fiat, Maruti, Mercedes, Bedford and Fargo but not necessarily in the same order. Only three people live above the floor on which A lives. Only one person lives between A and the one having a car Cadillac. F lives immediately below the one having a car Bedford. The one having a car Bedford lives on an even-numbered floor. Only three people live between the ones having a car Cadillac and Maruti. E lives immediately above C. E is not having a car Maruti. Only two people live between B and the one having a car Fargo. The one having a car Fargo lives below the floor on which B lives. The one having a car Fiat does not live immediately above D or immediately below B. D does not live immediately above or immediately below A. G does not have a car Ambassador. Question : How many people live between the floors on which D and the one having a car Bedford ?

A

One

B

Two

C

Three

D

Four

The screening of libraries us carried out by nucleic acid hybridisation and constitutes of following steps: i) Peeling of membranes carrying away bacterial cells with it ii) Cells are lysed and denaturing of DNA is being carried out iii) Hybridization with labelled DNA iv) Placing the membrane onto plate containing recombinant cells Choose the correct sequence in which the steps are carried out (starting to ending).

A

iv)-i)-ii)-iii)

B

iv)-ii)-i)-iii)

C

i)-ii)-iii)-iv)

D

iii)-ii)-i)-iv)

Which of the following statements are true?
Statement I Big data refers to no precise quantity, but generally refers to data in the range of Petabytes and Exabyte, i.e. billions to trillions of records, all from various sources. Big data is generated much faster. than traditional data in much larger quantities.
Statement II Big data interests industries because they are able to learn more patterns and curious variances than smaller data sets, with the capability to provide valuable insights into consumer behaviour, weather systems, financial market activity, or other phenomena.
Statement III Various departments and product lines use various applications within most organisations and store data in separate datasets. These separate databases may contain similar data, but data from one data base to another is not always consistent. This is called data silo.

A

Both statements I and II

B

Both statements II and III

C

Both statements I and III

D

All of the above

Which of the following statements are CORRECT when a protein sequence database is searched using the BLAST algorithm?
P. A larger E-value indicates higher sequence similarity.
Q. E-value -10 indicates sequence homology.
R. A higher BLAST score indicates higher sequence similarity.
S. E-value > 10^-10 indicates sequence homology.

A

P, Q and R only

B

Q and R only

C

P, R and S only

D

P and S only

In the blast furnace, as the oxygen percentage in air blast increases, the
P. flame temperature increases
Q. blast volume increases
R. blast volume decreases
S. flame temperature decreases

A

P, Q

B

P, R

C

R, S

D

Q, S

Screening is often carried out for a sequence that interacts with a protein for which already a clone is present. It is carried out in which host?

A

Bacterial host

B

Fungal host

C

Parasitic host

D

Yeast host

Choose the correct statement if the screening is carried out by screening by expression in vivo.

A

The proportion of recombinants carrying gene of interest is small

B

The recombinants carrying gene of interest don’t complement the host mutation

C

Mutation should be affecting many genes

D

Most of the products selected would be result of complementation

Each item consists of six sentences of a passage. The first and sixth sentences are given in the beginning as S1 and S6. The middle four sentences in each have been jumbled up and labelled as P, Q, R and S. You are required to find the proper sequence of the four sentences and markyour response accordingly on the Answer Sheet.
S1 :The dawn of the information age opened up great opportunities for the beneficial use of data.
S6 :To some, in this era of Big Data analytics and automated, algorithm-based processing of zettabytes of information, the fear that their personal data may be unprotected may conjure up visions of a dystopian world in which individual liberties are compromised.
P :But it is the conflict between the massive scope for progress provided by digital era and the fear of loss of individual autonomy that is foregrounded in any debates about data protection laws.
Q : It also enhanced the perils of unregulated and arbitrary use of personal data.
R : It is against this backdrop that the White Paper made public to elicit views from the public on the shape and substance of a comprehensive data protection law assumes significances.
S :Unauthorised leaks, hacking and other cyber crimes have rendered databases vulnerable.
The correct sequence should be

A

S Q R P

B

Q P R S

C

S R P Q

D

Q S P R

Consider the Assertion (A) and Reason (R) and select the correct answer:
Assertion (A) If one premise is particular, the conclusion must be particular.
Reason (R) (i) An affirmative particular has no distributed terms, and a negative particular has an only one.
(ii) The premises cannot both be particular and thus must differ in quantity.

A

A and R both are true but R (i) and (ii) correct explanations of A

B

A and R both are true but R (i) is correct explanation of A

C

A and R both are true but R (ii) is a correct explanation of A

D

A is true, but R (i) and (ii) are incorrect explanations of A

Libraries in which a particular sequence is present in one organism but are absent from another organism, are called as ___________

A

normalized libraries

B

subtractive libraries

C

selective libraries

D

partial libraries