In vitro, the apelin receptor serves as a coreceptor for the human immunodeficiency virus (HIV).

Correct Answer: True
In left ventricular dysfunction, Apelin is downregulated, is an adipokine, and improves insulin action in mouse insulin resistance models. The apelin receptor acts in vitro as a coreceptor for human immunodeficiency virus (HIV) and the peptides associated with apelin serve as HIV infection antagonists.