MZ B cells differentiate in which type of cells?

Correct Answer: Plasmablasts
MZ B cells differentiate into plasmablasts once they interact with antigens associated with macrophages or neutrophils. These plasmablasts produce large amounts of IgM antibody isotype. Along with IgM, MZ B cells also produce IgG and IgA by the mechanisms of class-switch recombination (CSR).