Which type of dendritic cells are considered to be perfect for cross-presentation?

Correct Answer: cDC1
Dendritic cells (DCs) are divided into two major categories: conventional DCs (cDCs) and plasmacytoid DCs (pDCs). Conventional DCs are again further classified into cDC1 and cDC2. In vivo, in humans and mice, it is observed that cDC1 plays a very important role in the cross-presentation mechanism and hence this DC subset is considered to be potent and perfect for cross-presentation of antigens.